Scoliosis Research Society (SRS)
An International Organization Dedicated to the Education, Research and Treatment of Spinal Deformity
Our Mission is to Foster Optimal Care for All Patients with Spinal Deformities
Because neuromuscular conditions are so varied in their clinical presentation, the actual pathophysiology (i.e. the set of events or process that ultimately brings about a condition) of scoliosis in these conditions is also varied. However, there are several features that are common across many, if not all, of the predisposing conditions.
Children with neuromuscular scoliosis usually do not experience any pain from the condition. The earlier the curve develops in neuromuscular scoliosis, the more likely it is to progress to a more severe curve. Likewise, the more severe a curve is when it is first detected, the faster it will progress, on average. Neuromuscular curves are often associated with a condition known as pelvic obliquity, in which the child's pelvis is unevenly tilted, with one side positioned higher than the other side.
Most children with neuromuscular scoliosis have poor balance and poor coordination of their trunk, neck, and head. There is also a high frequency of concurrent kyphosis, which is an abnormal forward-bending curve of the spine. The curves in almost all of the predisposing conditions have a high rate of progression, and almost all children will therefore require surgery at some point.