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Adolescent Idiopathic Scoliosis
There are significant efforts being made toward identifying the cause of AIS, but to date there are no well accepted causes for this particular type of scoliosis. The vast majority of patients are otherwise healthy and have no previous medical history. There are though many theories about the cause of AIS including hormonal imbalance, asymmetric growth and muscle imbalance. Approximately 30% of AIS patients have some family history of scoliosis, and therefore there seems to be a genetic connection. Many Scoliosis Research Society members are working to identify the genes that cause AIS, and this knowledge continues to expand at a rapid pace. Most likely, there will be many genes associated with scoliosis and each may be helpful in detecting scoliosis and determining the risk for progression of the curve.