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Scoliosis Research Society
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SRS: Scoliosis Research Society

Scoliosis Research Society

Dedicated to the optimal care of patients with spinal deformity

Grants Awarded

Since 1994, SRS, in conjunction with OREF and the Cotrel Foundation, have provided more than $3.8 million for spinal deformity research projects. Your contribution to the SRS Research Endowment Fund through OREF can help fund even more.

2016

Karina Zapata, PT, DPT, PhD
Scoliosis-specific exercises for at-risk mild adolescent idiopathic scoliosis curves: a multi-site preliminary randomized trial
$49,780 - 2 Years

David Gurd, MD
Computer Algorithm Software for Optimal Placement Pedicle Screws Considering Multiple Levels
$9,565 - 1 Year

Selina Poon, MD
Cadaveric Study of the Use of the Magnetic Expansion Control (MAGEC) Rod in the Magnetic Resonance Imaging Scanner
$15,000 - 1 Year

Ashish Patel, MD
Motion Analysis in the Axial Plane After Realignment Surgery for Adolescent Idiopathic Scoliosis
$25,000 - 1 Year

Xiaoyu Wang, PhD
Optimization of Implant Density in AIS Instrumentation Using a Computerized Spine Simulator
$25,000 - 1 Year

2015

Samer Adeeb, PhD, PEng
Markerless 3D Assessment of Severity and Progression of Scoliosis Using Surface Topography
$30,000 - 2 Years

Christopher Ames, MD
Prospective Multi-center Validation of Frailty Index, Deformity Surgical Invasiveness Index and Predictive Analytic Models for preoperatively predicting intraoperative and perioperative complications, LOS and EBL in ASD surgery
$25,000 - 2 Years

Sriram Balasubramanian, PhD
Structure and Growth of the Thoracolumbar Spine and Ribs in Normative Pediatric and AIS Subjects - A Comprehensive Multi-Center and Multi-Modal Validation Study
$50,000 - 2 Years

Ron El-Hawary, MD
The Effect of Spinopelvic Parameters on the Development of Proximal Junctional Kyphosis in Early Onset Scoliosis
$9,665 - 1 Year

Arin Ellingson, PhD
Biochemical and Mechanical Intervertebral Disc Profiles in Developmental Spinal Deformities
$25,000 - 2 Years

Kenny Kwan, MD
Three dimensional effects of bracing in adolescent idiopathic scoliosis
$10,000 - 1 Year

Mark Lee, MD
MidTerm Outcomes on Patients with Adolescent Idiopathic Scoliosis Following Spinal Fusion
$25,000 - 2 Years

Michael Lee, MD
The Influence of BMP9 expression on the development of scoliosis in a mouse model
$25,000 - 2 Years

Edmond Lou, PhD, PEng
Validation of 3D Ultrasound Measurements with EOS System on Children with AIS
$10,000 - 1 Year

Debabrata Patra
Investigating mechanisms of kyphoscoliosis in mice lacking Site-1 protease in osteochondroprogenitor cells.
$50,000 - 2 Years

Brian Varisco, MD
Induction of Lung Regeneration Following Posterior Spinal Fusion
$10,000 - 2 Years

2014

Saba Pasha, PhD
3D Biomechanical Analysis of the Spontaneous Lumbar Curve Correction after Selective Thoracic Fusion in Adolescent Idiopathic Scoliosis
$24,908.40 - 2 years

Carol Wise, PhD
Expanding AIS Gene Discovery: A Consortium-based Meta-analysis
$50,00.00 - 2 years

Melodie Metzger, PhD
The Impact of Type I Diabetes on Bone Metabolism and Growth after Spinal Fusion
$49,770.00 - 2 years

Jean-Marc Mac-Thiong, MD, PhD
Evidence-based Algorithm for the Surgical Treatment of Lumbosacral Spondylolisthesis
$49,988.00 - 2 years

Richard Gross, MD
Creating a Kyphotic Deformity Animal Model
$35,000.00 - 2 years

Sandra Saavedra, PT, PhD
Segmental Sensorimotor Control of Trunk Posture in Adolescent Idiopathic Scoliosis
$10,000.00 - 1 year

Jeffery P. Gorski, PhD
How Does SKI-1 Regulate Somitogenesis?
$25,000.00 - 2 year continuation awarded in 2014
$34,300.00 - 2 years - awarded in 2013

Ryan Gray, PhD
The Zebrafish Mutant Druk: A Model of Late-Onset Scoliosis
$25,000.00 - 2 year continuation awarded in 2014
$25,000.00 - 2 years - awarded in 2013

2013

Siram Balasubramanian, PhD
The True Patho-Anatomy of the Rib Hump in Adolescent Idiopathic Scoliosis and Its Influence of Future Surgical Intervention
$22,000.00 - 2 years

Nobuhiro Kamiya, MD, PhD
Impact of Cartilage-dependent Ras-MAPK Signaling on Scoliosis
$25,000.00 - 2 years

Dilip K. Sengupta, MD
Biomechanical Evaluation of a Dynamic Stabilization System for Prevention of Proximal Junction Kyphosis (PJK)
$10,000.00 - 1 year

Ryan Gray, PhD
The Zebrafish Mutant Druk: A Model of Late-Onset Scoliosis
$25,000.00 - 2 years
$25,000.00 - 2 year continuation awarded in 2014

Jeffery P. Gorski, PhD
How Does SKI-1 Regulate Somitogenesis?
$34,300.00 - 2 years
$25,000.00 - 2 year continuation awarded in 2014

Xu C. Liu, MD, PhD
Effect of Torque on Asymmetric Remodeling of the Vertebral Growth Plate
$25,000.00 - 2 years

Zhe Chen
Identification of Novel Loci Associated with Scoliosis Through Protein-Protein Interaction Studies
$25,000.00 - 2 years

Mario Romero-Ortega, PhD
Neuroprotection Against Oxidative Stress in an Animal Model of Distraction Spinal Cord Injury
$48,300.00 - 2 years

John M. Popovich, Jr., PhD, DPT
The Effects of Asymmetrical Spinal Muscle Impairment on the Development of Scoliosis: Morphological, Biomechanical and Histological Properties of the Spine
$9,981.00 - 1 year

Susan M. Goobie, MD, FRCPC
The Efficacy and Pharmacokinetic/Pharmacogenetic Profile of Intravenous Tranexamic Acid in Decreasing Blood Loss in Pediatric Idiopathic Scoliosis Surgery
$50,000.00 - 2 years

Ann M. Hayes, PT, DPT, OCS
What is the Clinical Significance of Measuring Lumbopelvic Position?
$10,000.00 - 1 year

2012

Michael J. Yaszemski, MD
Directed Research Grant Winner
Long-term Pulmonary Function, Health-related Quality of Life, and Sagittal Plane Alignment Following the Treatment of Adolescent Idiopathic Scoliosis
$86,384.00 - 2 years

Kathy J. Simpson, PhD
Movement Techniques Used by Individuals with Adolescent Idiopathic Scoliosis (AIS) during High-Effort Activities and the Effects of Spinal Fusion Surgery on Compensatory Adaptations
$9,846.00 - 1 years

Mikkel O. Andersen, MD
Adolescent Idiopathic Scoliosis in Twins -- A Study Based on the Danish Twin Registry
$39,086.00 - 2 years

Michael G. Vitale, MD, MPH
Spine-Based vs. Rib-Based Anchors in Growth-Sparing Constructs for Young Children with Scoliosis
$45,516.00 - 2 years

Samer M. Adeeb, PhD, P.Eng
A Novel Approach to Use Surface Topography Results for Assessing Scoliosis
$25,000.00 - 2 years

Julio Domenech, MD, PhD
Study of Neural Connectivity, Functional Activation and Grey Matter Volume of the Sensorimotor Network in Idiopathic Scoliosis
$32,000.00 - 2 years

Benjamin D. Roye, MD, MPH
Validation of a Genetic Test to Predict the Risk of Curve Progression in Adolescent Idiopathic Scoliosis
$25,000.00 - 2 years

Michelle C. Caird, MD
Treatment of the Growing Spine with Bisphosphonates: Mechanical Properties and Healing
$10,000.00 - 1 years

Hong Zhang, MD
Primary Initiator of Scoliosis: A Pilot Study in an Immature Porcine Model
$41,920.00 - 2 years

Patrick Bosch, MD
Coagulation in Scoliosis Surgery
$20,000.00 - 2 years

2011

Frank L. Acosta, Jr., MD
Improving Bone Formation in Osteoporosis through Mechanical Signaling Pathways
$10,000 - 1 year

Diana Glaser, PhD
Real-Time Analysis of the Biomechanics and the Effectiveness of Fusionless Spinal Growth Modulation Devices
$25,000.00 - 2 years

Ahmad Nassr, MD
Vertebral Fracture Prediction Finite Element Model of the Human Osteoporotic Spine Using Novel Computational and Experimental Validation Approaches
$25,000.00 - 2 years

Peter O. Newton, MD
Three Dimensional Visualization of Vertebral Growth Cartilage and Disc; the Effects of Growth Modulation
$9,987.00 - 1 year

Shunmoogum A. Patten, PhD
Genetic Determinants of Vestibular Dysfunction in AIS
$10,000.00 - 1 year

Rachel Wervick, PhD
Etiology of Scoliosis in a Mouse Model of Prader-Willi Syndrome
$100,000.00 - 2 years

Melodie Metzger, PhD
The Relationship between Serum Vitamin D levels, Successful Fusion and Fusion Strength: A Quantitative Analysis
$10,000.00 - 1 year

Virginie Lafage, PhD
Classification for Adult Spinal Deformity
$43,420.00 - 2 years

Paul Gerdhem, MD, PhD
Exome Sequencing in Patients with Idiopathic Scoliosis
$25,000.00 - 2 years

Leon E. Kaplan, MD
The Effect of Scoliosis Surgical Correction on Sexual Activity, Pregnancy and Child Delivery
$10,000.00 - 1 year

Richard Gross, MD
Kyphosis and Implantation: Modeling a Clinical Phenomenon
$25,000.00 - 2 years

Antonia Chen, MD, MBA
Comprehensive Screening Protocal for Methicillin-resistant Staphylococcus Aureus (MRSA) and Methicillin-sensitive Staphylococcus Aureus (MSSA) in the Spine
$24,967.00 - 2 years

2010

Lisbet Haglund, PhD
The influence of asymmetric loading on the structure and metabolism of the human invertebral disc
$25,000 - 2 years

Michelle Marks, PT, MA
Prospective Study of Motion Preservation Evaluation below Fusions of the Spine in Adolescent Idiopathic Scoliosis
$24,954 - 2 years

Delphine Perie-Curnier, PhD
Toward the etiology of Idiopathic Scoliosis using the distribution patterns of quantitative MR parameters within the intervertebral discs as predictive factors of progression
$25,000 - 2 years

Eric Varley, DO
Growth Plate and Intervertebral Cellular Responses to Spinal Growth Modulation with Asymmetric Tether: A Pilot Study in a Immature Porcine Model
$10,000 - 1 year

Kelvin Yeung, MD
"SMART" internal spinal orthosis for gradual correction of spinal deformities
$24,954 - 2 years

Phillip F. Giampietro, MD, PhD
Identification of a Locus for Idiopathic Scoliosis on Chromosome 12p
$100,000 - 2 years

Guang-Qian Zhou, MD, PhD
Molecular Analysis of the BMP-7 Action of Intervertebral Disc Cells
$25,000 - 2 years

Nobuhiro Kamiya, MD, PhD
Impact of Cartilage-dependent Ras-MAPK Signaling on Scoliosis
$25,000 - 2 years

Eric Parent, PhD
A Pilot Study for a Randomized Control Trial to Develop a Prediction Rule to Identify Patients with Adolescent Idiopathic Scoliosis and Schroth Curve Type 3c who will Respond to Schroth Exercises
$10,000 - 1 year

2009

Kirkham Wood, MD
Correlation of Adjacent Segment Degeneration and Quality of Life Outcome: Application an In-vivo Biomechanics to Assess the Effect of Fusion in AIS
$50,000 - 2 years

Hongbo Liu, MD
United States' trends and regional variations in Lumbar Spine surgery for children with spondylolysis and spondylolisthesis
$10,000 - 1 year

2008

Shane Burch, MD
Monitoring of Nerve Root Injury Using Transcranial Motor-Evoke Potentials in a Pig Model
$23,255 – 2 years

Andrew Briggs, MD
Measurement of Vertebral Subregional Bone Mineral Density using Lateral-Projection DXA: Establishing Concurrent and Predictive Validity
$10,000 – 1 year

Daniel Y.T. Fong, MD
Single-Blind Comprehensive Cohort Study Incorporating A Randomized Controlled Design on Bracing in AIS: A Feasibility Study
$25,000 – 2 years

David Aronsson, MD
The Contribution of Asymmetric Growth and Vertebral Remodeling to Apical Wedging
$41,829 – 2 years

Qian Chen, PhD
The Potential Role of Fibronection in the Pathogenesis of Congenital Scoliosis
$25,000 – 1 year

Carol Wise, PhD
Identification of Genetic Susceptibility in Idiopathic Scoliosis
$60,000 – 1 year

Sigurd Berven, MD
Impact of Spinal Disorders on Health Related Quality of Life
$5,000 - 1 year

Safdar Khan, MD
Utilizing a Novel MRI-based (Dense-FSE) Technique to Characterize Spatial Strain Distributions in an Established Model of Intervertebral Disc Degeneration: Implications for Tissue Engineering
$10,000 - 1 year

Hubert Labelle, MD
Towards a 3D Classification of Adolescent Idiopathic Scoliosis
$49,600 - 2 year

2007

Jeffrey Shilt, MD & Peter Apel, MD
Temporary unilateral paraspinal muscle paralysis on the prevention and progression of scoliosis: Investigation in a chicken model
$9,740

Mohammed Diab, MD
Comparison of Extended-Release Epidural Morphine, Patient-Controlled Epidural Analgesia and Patient-Controlled Intravenous Analgesia for Postoperative Pain after Posterior Spinal fusion in Adolescents
$24,245

Frank Schwab, MD
Adult Deformity: Development of an Effective Treatment Algorithm Based upon Outcomes Analysis
$50,000 – 2 years

John Lonstein, MD
Long-term Function Outcomes of Early Fusions for Congenital Scoliosis
$75,450 – 2 years

Michael Vitale, MD
CT Analysis of Pedicle Screw Placement in Pediatric Patients
$20,595 – 1 year

Vidyadhar Upasani, MD
The Effect of Increasing Construct Rigidity on Intervertebral Disc Health: A Pilot Study in a Porcine Anterior Spinal Growth Modulation Model
$10,000– 1 year

Xudong Li, MD
Nucleus Pulposus Regeneration with Genetically Engineered Fat-derived Stem Cells
$50,000 – 2 years

Josh Auerbach, MD and John P. Dormans, MD
An in vivo Porcine Animal Model to Detect Spinal Cord Vascular Flow in Spinal Deformity Surgery using Transcranial Motor Evoked Potential Monitoring
$10,000 – 1 year

2006

Carol Wise, PhD
Identification of Genetic Susceptibility in Idiopathic Scoliosis
$19,000 - 2 years

Shane Burch, MD FRCSC
The Role of Hypoxic Stress on the Vertebral Growthplates of the Developing Spine and its Potential Role in Pathogenesis of Scoliosis
$10,000 - 1 year

Vedat Deviren, MD
The Minimal Clinically Important Difference (MCID) for Spinal Disorders: Finding the Threshold of Clinically Significant Change
$24,996 - 1 year

2005

Kenneth Cheung, MD
Surface Modification of Nitinol by Plama Immersion ION Implantation
$100,000 - 2 years

Robin Patel, MD
Biofilms and Spinal Instrumentation
$99,850 - 2 years

Alf Nachemson, MD, PhD
A Continuation of the "SRS Study for Brace Treatment of Adolescent Idiopathic Scoliosis" - Follow-up of the Swedish Patients at Least 10 Years After Maturity
$47, 020 - 2 years

Brian Snyder, MD, PhD
How does VEPTR Affect Pulmonary Function: An In-vivo Assessment using the Rabbit Scoliosis Model
$34,408 - 1 year

Stefan Parent, MD, PhD
Analysis of Local 3-D Measurements of the Curve as Predictive Factors for Curve Progression in AIS
$25,000 - 1 year

Francis Shen, MD
Can We Eliminate the Need for Autologous Bone Graft Harvest? The Use of Multipotential Adipose-derived Stromal Cells in an Activated Matrix for Posterolateral Spinal Fusions
$25,000 - 1 year

Andrew Merola, MD
Association between an Aggrecan Gene Polymorphism and AIS
$10,000 - 1 year

Anthony Florschutz. MD
Experimental Scoliosis Using Vertebral Body Implanted Magnets in an Immature Goat Model
$10,000 - 1 year

Stefan Parent, MD, PhD
Growth Modulation of the Chest Case in a Pre-Natal Ovine Model: A Preliminary Study
$10,000 - 1 year

Andrew Mahar, MS
How Does Increasing Curve Magnitude in Scoliotic Deformity Affect the Biomechanics of the Spine with Implications Toward Curve Correction?
$10,000 - 1 year

Donita Bylski-Austrow, PhD
Mechanbiology of Growth: In-Vivo Growth Plate Pressures
$10,000 - 1 year

Felix Breden, BA, MSc, PhD
The Guppy 'Curveback' Mutant as a Model for Spinal Deformity
$10,000 - 1 year

Jack C.Y. Cheng, MD
Abnormal Differential Longitudinal Growth of Vertebral Column and Spinal Cord in AIS - A Morphological and Functional Study
$77,000 (Cotrel)

Brian K. Kwon, MD, PHD, FRCSC
Neuroprotection for Acute Spinal Cord Injury: The Preclinical Evaluation of Drugs That Are Currently Used in Human Non-Spinal Applications
$24,881.60 - 2 years

2004

Philip Giampietro, MD, PhD
Mutation Analysis is Human Congenital Scoliosis and Vertebral Malformations
$77,077 - 2 years

Carol Wise, PhD
Localization and Analysis of Candidate Genes for Idiopathic Scoliosis
$50,000 - 2 years

Ralph Marcucio, PhD
A Comparison of the Expressions of Malatonin, Calmodulin and 5-HT4 in Paravertebral Muscle and Platelets of Patients with our without Adolescent Idiopathic Scoliosis
$50,000 - 2 years (Cotrel)

2003

Jack. C.Y. Cheng
Are VDR, Era and PTHR1 Genes Associated With The Occurrence as well As Abnormality In Bone Growth And Sexual Maturation In Adolescent Idiopathic Scoliosis
$70,800 - 2 years

John Kostuik, MD
Adult Onset of Scoliosis: Relationship between Osteoporosis and Deformity
$30,000 - 2 years

Matthew Dobbs, MD
Idiopathic Scoliosis: Gene Mapping Identification
$47,177 (Cotrel)

2002

Carol Wise, PhD
Localization & Analysis of Candidate Genes of Idiopathic Scoliosis
$36,666.50 - 2 years (Cotrel)

2001

Jack C.Y. Cheng, MD
Relationship between Postural Balance, Somatosensory Evoked Potential and the Progression of Scoliotic Deformity in the AIS
$70,800 - 2 years (Cotrel)

2000

Keith Bagnall, PhD
The Relationship Between Serum Melatonin & Growth Hormone in Pinealectomy Model
$14,250.00 - 2 years

Oheneba Boachie-Adjei, MD
w/ Dr. Raymond Clarke
Developmental Basis of the Klippel-Feil Syndrome
$60,000 - 3 years

Frances Farley, MD
Prediction of Curve Progression in Congenital Scoliosis Using a Mouse Model
$44,926 - 2 years

Carol A. Wise, PhD
Localization of a Gene for Susceptibility To Idiopathic Scoliosis
$36,066.50 - 2 years

Nancy Hadley Miller, MD
Genetic Linkage of Familial Idiopathic Scoliosis - A Complex Orthopaedic Disorder
$50,000 - 2 years

Thomas Lowe, MD
Platelet Calmodulin Levels in AIS: A Predictor of Curve Progression and Severity
$42,070 - 2 years

1999

Jack C.Y. Cheng, MD
The Loss of Synchronous Coupling of Endochrondral and Membranous Ossification in AIS: The Morphological and Biological
Evidences
$35,400 - 1 year

James O. Sanders, MD
A Determination of Maturity in Girls with Idiopathic Scoliosis: A Pilot Study
$48,252 - 2 years

1998

Nancy Hadley Miller, MD
Genetic Anaylsis of Etiologic Factors of AIS
$50,000 - 2 years

John A. Szivek, PhD
Monitoring Spinal Fusion in Scoliosis Patients: A Biomechanical & In Vivo Study
$54,000 - 2 years

Jack Engsberg, PhD
Comparison of Outcome Measures in Adult Scoliosis Patients Undergoing an Extended Spinal Fusion to L5 or Sacrum or Revision of Previous Long Spinal Deformity Fusion
$80,308 - 3 years

William A. Vannah
Longitudinal Study of Balance & Other Factors in AIS
$10,887.50 - 2 years